Level of Evidence Pyramid for Systematic Reviews
What the levels of evidence pyramid means in systematic reviews — plain diagram language plus a worked example level.
Read articleResearch PDFs in. Defensible tables out.
Extract structured answers for systematic reviews, meta-analyses, and CERs with verbatim quotes, page locations, and review flags in every Excel export.
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In the PDF
Four example answers from one open-access trial. The highlight is the sentence behind the answer.

Preview shows the sample-size sentence.
Starling et al., JAMA Network Open, 2024. Voice-Activated Cognitive Behavioral Therapy for Insomnia. DOI · CC BY 4.0. © 2024 Starling CM et al. Highlights added; answers paraphrased. Open the sample PDF.
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Receive structured Excel plus an Audit Trail sheet: quotes, locations, confidence, flags.
Upload multiple papers and extract against the same question set—ideal for screening follow-ups and living reviews.
Smith_2023_RCT.pdf
12 pages
Chen_2022_Cohort.pdf
18 pages
Garcia_2024_Meta.pdf
24 pages
Consistent columns for filtering and synthesis—plus a second sheet that keeps every answer accountable.
Results and Audit Trail ship together - verbatim quotes, page locations, confidence scores, and review flags so the table stays defensible.
| Question | Verbatim | Location | Conf. | Flag |
|---|---|---|---|---|
| Mean age | "The mean age of the study population was 64.5 ± 8.2 years at baseline." | Results · Table 1 Page 4 | 98% | Verified |
| Follow-up duration | "Participants were followed for a median of 24 months (IQR 18–30)." | Methods · §2.3 Page 2 | 95% | Verified |
| Sample size | "A total of 412 patients met eligibility and were included." | Abstract Page 1 | 99% | Verified |
| Primary endpoint | "Outcome data not explicitly reported in Table 4." | Results · Table 4 Page 12 | N/A | Not found |
| Intervention | "Active treatment with an SGLT2 inhibitor compared with matched placebo." | Methods · Interventions Page 3 | 81% | Needs review |
| Comparator | "Control participants received matched placebo tablets." | Methods · §2.1 Page 3 | 96% | Verified |
| Adverse events | "Safety events were described narratively without a consistent severity scale." | Results · Safety Page 9 | 74% | Ambiguous |
Every cell can point back to the source language, the page it came from, and a status flag when the paper is silent or ambiguous.
Table 1 summarizes demographic and clinical characteristics. The mean age of the study population was 64.5 ± 8.2 years at baseline. Sixty-two percent of participants were male.
Live audit signals
Guides on evidence tables, systematic reviews, and HEOR workflows.
What the levels of evidence pyramid means in systematic reviews — plain diagram language plus a worked example level.
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